Mesenchymal Stem Cells in Synovial Fluid Increase After Meniscus Injury

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Mesenchymal Stem Cells in Synovial Fluid Increase After Meniscus Injury

BACKGROUND Although relatively uncommon, spontaneous healing from a meniscus injury has been observed even within the avascular area. This may be the result of the existence of mesenchymal stem cells in synovial fluid. QUESTIONS/PURPOSES The purpose of this study was to investigate whether mesenchymal stem cells existed in the synovial fluid of the knee after meniscus injury. METHODS Synovi...

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Synovial fluid-derived mesenchymal stem cells increase after intra-articular ligament injury in humans.

OBJECTIVE The existence of mesenchymal stem cells (MSCs) in SF was previously reported. However, the behaviour and properties of MSCs derived from SF have not been fully elucidated. METHODS Human SFs were obtained from 19 knee joints with anterior cruciate ligament injury around the time of reconstruction surgery, and from three healthy volunteers. SF was plated, cultured and examined for col...

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Human mesenchymal stem cells in synovial fluid increase in the knee with osteoarthritis

INTRODUCTION: The existence of mesenchymal stem cells (MSCs) in synovial fluid was first reported in 2004 [1]. The same group further reported in 2008 that MSCs in synovial fluid numerically increased in early osteoarthritis [2]. This paper is interesting because it sheds light on roles of MSCs in synovial fluid. However, the design of the study seemed to be inappropriate. All synovial fluid ex...

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Synovial fluid-derived synovial fragments represent an improved source of synovial mesenchymal stem cells in the temporomandibular joint

Surgery-obtained synovium specimens (SSSs) can provide a source of synovial mesenchymal stem cells (SMSCs) for experimental studies. However, these specimens contain diverse tissues, including the intima and subintima; therefore, these SMSCs are not entirely derived from the intima and their cell source is heterogeneous. The present study isolated synovial fragments (SFs) from synovial fluid di...

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Background: Spinal cord has a limited capacity to repair therefore, medical interventions are necessary for treatment of injuries. Transplantation of Schwann cells has shown a great promising result for spinal cord injury (SCI). However, harvesting Schwann cell has been limited due to donor morbidity and limited expansion capacity. Furthermore, accessible sources such as bone marrow stem cells ...

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ژورنال

عنوان ژورنال: Clinical Orthopaedics & Related Research

سال: 2014

ISSN: 0009-921X

DOI: 10.1007/s11999-013-3418-4